18 results
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Common Diabetes Medications ... GLP-1 Receptor Agonists ... • DPP4i / Gliptins ... #pharmacology # ... pathophysiology #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... GLP-1 receptor agonists ... events TZDs DPP ... comparison #management #endocrinology ... #dm2
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... GLP-I receptor agonist ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + DPP4 ... dapagliflozin) Dpp4 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
different than other medications ... very tolerable medication ... Renal #Dosing #Pharmacology ... Management #Diabetes #DM2 ... #Endocrinology
Profiles of Antidiabetic Medications - AACE 2018 

#Antidiabetic #Medications #Profiles #SideEffects #Table #DecisionAid #Orals #DM2 #Diabetes
of Antidiabetic Medications ... #Antidiabetic #Medications ... DecisionAid #Orals #DM2 ... #Diabetes #Endocrinology ... #Pharmacology #
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
commonly used medications ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Type 2 Inpatient Medication ... Sulfonylurea, TZD, DPP ... GLP-1 receptor agonist ... #pharmacology # ... comparison #table #endocrinology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
- PPAR gamma agonist ... AGENTS • GLP-1 agonists ... (Adlyxin) • DPP ... by inhibiting DPP ... Diabetes #Management #pharmacology
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
Opioid Use Disorder Medications ... which higher doses do ... margin of safety in pharmacology ... #UseDisorder #Medications ... Comparison #Table #Pharmacology