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Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Sulfonylureas GLP-1 receptor ... agonists - ↓ major ... events TZDs DPP ... #endocrinology ... #dm2
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... therapy with GLP-I receptor ... agonist • Personal ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... agonist, SGLT2i ... Diabetes #Mellitus #DM2 ... #comparison #table ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... Ozempic), or daily tablet ... #Agonists #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Sedative-Hypnotic Drugs
Benzodiazepines:
 - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
including sedation and relief ... Agonist: Mechanism ... uncertain: - Partial agonist ... #medications #pharmacology ... #comparison #table
Opioid Use Disorder Medications - Pharmacokinetics

Buprenorphine is a partial mu-opioid receptor agonist with low intrinsic activity,
which higher doses do ... margin of safety in pharmacology ... the sublingual tablet ... Pharmacokinetics #Comparison ... #Table #Pharmacology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal tunnel ... Lanreotide) ± GH receptor ... Pegvisomant) ± D2 ... agonist (Carbergoline ... Diagnosis #Management #Endocrinology