17 results
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
and DOACs VKA, ... Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... , Betrixaban, DOAC ... #DOACs #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Kcentra) - Heparin/LMWH ... Protamine sulfate - Dabigatran ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Hepatic, 25% Renal Dabigatran ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #INR #heparin #LMWH ... #NOAC #warfarin ... #coumadin #rivaroxaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Pathophysiology Anticoagulation ... warfarin) for chronic anticoagulation ... accelerates the bridging ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... AFib: CrCl 15-50 ... @Bloodman #DOAC ... #Dabigatran #Edoxaban ... #NOAC
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
and rivaroxaban ... filtration rate; DOAC ... ; LMWH = low molecular ... #DOAC #VTE #Malignancy ... #Anticoagulation
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... : • Apixaban, Edoxaban ... or Rivaroxaban ... not available #DOAC ... #Reversal #NOAC
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Tests PT / INR, aPTT ... Warfarin UFH LMWH ... Fondaparinux Rivaroxaban ... Apixaban, Edoxaban ... Argatroban Dabigatran