11 results
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... , Parenteral anticoagulant ... #DOACs #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #Oral #Anticoagulant ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... #Anticoagulant ... #DOAC #Management ... #Table #Pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 80% Renal Edoxaban ... #Pharmacology #
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #Xarelto #apixaban ... #Pradaxa #management ... #pharmacology #
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
AFib: CrCl 15-50 ... #CheatSheet #Dosing ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... or a new oral anticoagulant ... traditional oral anticoagulant ... : A new oral anticoagulant ... #Dabigatran #Apixaban
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Perioperative Management ... direct acting oral anticoagulants ... to assess for anticoagulant ... , Edoxaban, Rivaroxaban ... #pharmacology #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
procedure Stop anticoagulant ... Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... #Oral #anticoagulant ... #pharmacology