11 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... Rivaroxaban - Apixaban ... h) #Warfarin #DOAC ... NOAC #comparison ... #rivaroxaban #apixaban
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Loading #DVT #Pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 0% Renal Apixaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology # ... #anticoagulation
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... @Bloodman #DOAC ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban ... #NOAC
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... , Edoxaban, Rivaroxaban ... DeLoughery @Bloodman #DOAC ... #anticoagulation
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... Anticoagulant #DOAC ... #Pharmacology #
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... , Edoxaban or Rivaroxaban ... not available #DOAC ... #Reversal #NOAC ... #pharmacology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
, rivaroxaban - ... #anticoagulation ... #pharmacology # ... medications #doac ... #comparison #table
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
accelerates the bridging ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... determine timing of DOAC ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban ... postoperative #DOAC