13 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... #Dosing #Oral #Anticoagulant ... #Anticoagulation ... Pharmacology #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... , Betrixaban, DOAC ... , Parenteral anticoagulant ... JAHA.120.017559 #Anticoagulants ... #DOACs #anticoagulation
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Protamine sulfate - Dabigatran ... Betrixaban (Bevyxxa), Edoxaban ... #doac #noac #pharmacology ... #hematology #reversal
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
direct-acting oral anticoagulants ... filtration rate; DOAC ... direct-acting oral anticoagulant ... #DOAC #VTE #Malignancy ... #Anticoagulation
Oral Anticoagulation - VTE and DVT Bridging

- Amelia Furbish PharmD Student @ https://www.instagram.com/happypillsrx/

#DOAC #Oral #Anticoagulant #VTE
Oral Anticoagulation ... - VTE and DVT Bridging ... happypillsrx/ #DOAC ... #Oral #Anticoagulant ... #VTE #DVT #Bridging
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology #
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... - Atrial Fibrillation ... @Bloodman #DOAC ... #Hematology #Pharmacology ... #Edoxaban #NOAC
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... or a new oral anticoagulant ... traditional oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #Fondaparinux #NOAC
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... from Warfarin to DOAC ... Kfischer_10 #Anticoagulant ... #Bridging #anticoagulation