12 results
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... and DOACs VKA, ... Dabigatran, Rivaroxaban ... , Betrixaban, DOAC ... #DOACs #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Rivaroxaban #Edoxaban ... #Hematology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
of Oral Anticoagulant ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... #Pharmacology # ... Clearance #oral
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
anticoagulants ... (DOACs) with randomized ... filtration rate; DOAC ... anticoagulant; ... #DOAC #VTE #Malignancy
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... , Rivaroxaban ... #Anticoagulant ... #DOAC #Management ... #Table #Pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... Protamine sulfate - Dabigatran ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... @Bloodman #DOAC ... #Hematology #Pharmacology ... #Dabigatran #Edoxaban ... #NOAC
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
of DOACs Problem ... anticoagulants ... to assess for anticoagulant ... determine timing of DOAC ... postoperative #DOAC
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants ... anticoagulants ... : A new oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #NOAC #Mechanism