11 results
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... , Betrixaban, DOAC ... #DOACs #anticoagulation
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... #Dosing #Oral #Anticoagulant ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... PCC (Kcentra) - Heparin ... (Praxbind) - Apixaban ... #doac #noac #pharmacology ... #hematology #reversal
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Clearance of Oral Anticoagulant ... , 0% Renal Apixaban ... 80% Renal Edoxaban ... 35% Renal #DOAC ... #NOAC #Metabolism
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... , Edoxaban or Rivaroxaban ... #Reversal #NOAC ... #Oral #anticoagulant
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... or a new oral anticoagulant ... #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
and rivaroxaban ... direct-acting oral anticoagulants ... filtration rate; DOAC ... direct-acting oral anticoagulant ... #DOAC #VTE #Malignancy
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... @Bloodman #DOAC ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban ... #NOAC
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... , rixaroxaban, apixaban ... and edoxaban. ... thrombin time #doac ... #noac #anticoagulation
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
consider withholding anticoagulant ... decision to continue anticoagulant ... DOAC, direct oral ... anticoagulant; ... #DOAC #VTE #Malignancy