11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Switching Between Anticoagulants ... Dabigatran, Rivaroxaban ... , Apixaban, Edoxaban ... , Betrixaban, DOAC ... #DOACs #anticoagulation
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Anticoagulants Common ... (Praxbind) - Apixaban ... (Lixiana), Rivaroxaban ... #doac #noac #pharmacology ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Dosing: Apixaban ... @Bloodman #DOAC ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban ... #Dabigatran #Edoxaban
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
direct-acting oral anticoagulants ... filtration rate; DOAC ... direct-acting oral anticoagulant ... #DOAC #VTE #Malignancy ... #Management #Hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... procedure Stop anticoagulant ... , Edoxaban or Rivaroxaban ... #Oral #anticoagulant ... #hematology #management
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
and Novel Oral Anticoagulants ... or a new oral anticoagulant ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #NOAC #Mechanism
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
of Direct Oral Anticoagulants ... , rixaroxaban, apixaban ... and edoxaban. ... thrombin time #doac ... #noac #anticoagulation
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral anticoagulants ... to assess for anticoagulant ... determine timing of DOAC ... , Edoxaban, Rivaroxaban ... postoperative #DOAC
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
consider withholding anticoagulant ... DOAC, direct oral ... anticoagulant; ... #DOAC #VTE #Malignancy ... #Management #Hematology