11 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Sheet: Warfarin, Apixaban ... , Dabigatran, Rivaroxaban ... #Anticoagulant ... #DOAC #Management ... #Table #Pharmacology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
- Atrial Fibrillation ... Renal Dosing: Apixaban ... @Bloodman #DOAC ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
Anticoagulant specific ... #anticoagulation ... #clotting #INR ... rivaroxaban #Xarelto #apixaban ... #Eliquis #dabigatran
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
the mainstay of VTE ... accelerates the bridging ... #Pharmacology #Pathophysiology ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
in North America ... per treatment table ... of Therapy • Dabigatran ... inhibitor) • Apixaban ... Management #Treatment #pharmacology
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Quick tip: apixaban ... and dabigatran ... Transitioning #Anticoagulation ... #Pharmacology # ... Table
Cardiac Valve Replacement - Anticoagulation INR Targets and Antiplatelet by Valve Type

Bioprosthetic valves require at least
utilize direct oral anticoagulants ... patients with chronic atrial ... #Management #Cardiology ... #Target #DOAC # ... Table #Replacement
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
typically needed • DOACs ... thrombin inhibitor (dabigatran ... (rivaroxaban, apixaban ... Warfarin: therapeutic INR ... diagnosis #management #cardiology
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
Anticoagulant Therapy ... due to use of DOAC ... clinical trials ... Triple #therapy #anticoagulation ... #PCI #pharmacology