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anticoagulation pharmacology management hematology table anticoagulant cardiology oral diagnosis dosing reversal rivaroxaban anticoagulants vte warfarin afib comparison edoxaban heparin algorithm
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet Novel (or Direct) Oral Anti-Coagulants • Rivaroxaban • Apixaban
NOAC / DOAC Pharmacology ... Rivaroxaban • Apixaban ... • Dabigatran ... #NOAC #DOAC #Pharmacology
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Warfarin and DOAC ... Rivaroxaban - Apixaban ... h) #Warfarin #DOAC ... #Pharmacology #NOAC ... #rivaroxaban #apixaban
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Protamine sulfate - Dabigatran ... (Praxbind) - Apixaban ... anticoagulation #doac ... #noac #pharmacology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
Hepatic, 0% Renal Apixaban ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Renal Dosing: Apixaban ... @Bloodman #DOAC ... #Pharmacology #Apixaban ... #Edoxaban #NOAC
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... Antidotes: • Apixaban ... modified factor Xa • Dabigatran ... not available #DOAC ... #Reversal #NOAC
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
concentrations of dabigatran ... , rixaroxaban, apixaban ... thrombin time #doac ... #noac #anticoagulation
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #Fondaparinux #NOAC
Switching Between Anticoagulants and DOACs VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant DOI: 10.1161/JAHA.120.017559 #Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... VKA, Dabigatran ... , Rivaroxaban, Apixaban ... Edoxaban, Betrixaban, DOAC ... Anticoagulants #DOACs
DOAC Cheat Sheet • Apixaban, Dabigatran, Edoxaban, Rivaroxaban • Renal Dosing • Common Drug interactions •
DOAC Cheat Sheet ... • Apixaban, Dabigatran ... DeLoughery @Bloodman #DOAC
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