15 results
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Primary Routes of Clearance ... of Oral Anticoagulant ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #oral #anticoagulation
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... management #Direct #Oral
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Apixaban (25% renal clearance ... patients 5mg bid Dabigatran ... @Bloodman #DOAC ... #Rivaroxaban #Dabigatran
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... Bridging #Dosing #Oral ... Anticoagulation #Dabigatran
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban
 - Mechanism of Action
 - Routine Blood
Oral Anticoagulation ... Warfarin, Apixaban, Dabigatran ... - Resume #Oral ... Anticoagulant #DOAC
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... direct acting oral ... anticoagulants (DOACs ... recent creatinine clearance ... of Therapy • Dabigatran
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... direct-acting oral ... anticoagulants (DOACs ... direct-acting oral ... #Cancer #Algorithm
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Fondaparinux, and Novel Oral ... subcutaneous) and oral ... Heparins #LMWH #UFH #DOAC ... #Dabigatran #Apixaban ... #Fondaparinux #NOAC
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... modified factor Xa • Dabigatran ... not available #DOAC ... #Reversal #NOAC ... #Oral #anticoagulant
Hypoglycemia - Evaluation Algorithm
Interpreting Hypoglycemia Labs - the patient must be hypoglycemic at the time of
Hypoglycemia - Evaluation Algorithm ... Exogenous Insulin Oral ... → Oral Hypoglycemic ... Hypoglycemia #Evaluation #Algorithm ... workup #diagnosis #endocrinology