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NOAC / DOAC Pharmacology and Prescribing Cheat Sheet Novel (or Direct) Oral Anti-Coagulants • Rivaroxaban • Apixaban
NOAC / DOAC Pharmacology ... Novel (or Direct) Oral ... • Apixaban • Dabigatran ... #Prescribing #hematology ... management #Direct #Oral
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... Clotmaster #VTE #DOAC ... Bridging #Dosing #Oral ... Anticoagulation #Dabigatran ... #Pharmacology #Hematology
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... modified factor Xa • Dabigatran ... not available #DOAC ... #Oral #anticoagulant ... #hematology #management
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... concentrations of dabigatran ... thrombin time #doac ... #noac #anticoagulation ... #hematology #laboratory
Switching Between Anticoagulants and DOACs VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant DOI: 10.1161/JAHA.120.017559 #Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... VKA, Dabigatran ... Edoxaban, Betrixaban, DOAC ... Anticoagulants #DOACs ... anticoagulation #Switching #hematology
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents Warfarin - 100% Hepatic, 0% Renal Apixaban
of Clearance of Oral ... Hepatic, 25% Renal Dabigatran ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism ... Pharmacology #Clearance #oral
Warfarin and DOAC Pharmacology Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban Target - Prodrug - Bioavailability
Warfarin and DOAC ... Pharmacology Warfarin - Dabigatran ... h) #Warfarin #DOAC ... #Pharmacology #NOAC ... comparison #table #dabigatran
Anticoagulants Common Reversal Agents - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra) - Heparin/LMWH
Protamine sulfate - Dabigatran ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing Renal Dosing: Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... patients 5mg bid Dabigatran ... @Bloodman #DOAC ... Anticoagulation #Hematology ... #Rivaroxaban #Dabigatran
Oral Anticoagulation Management Cheat Sheet: Warfarin, Apixaban, Dabigatran, Rivaroxaban - Mechanism of Action - Routine Blood
Oral Anticoagulation ... Warfarin, Apixaban, Dabigatran ... - Resume #Oral ... Anticoagulant #DOAC
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