25 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... Rivaroxaban - Apixaban - Edoxaban ... h) #Warfarin #DOAC ... #Pharmacology #NOAC ... #comparison #table
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... Rivaroxaban #Dabigatran #Edoxaban ... #NOAC
Direct-acting oral anticoagulants (DOACs) for VTE treatment and prevention - Comparison Table

#DOAC #Anticoagulants #Anticoagulation #VTE #Management
anticoagulants (DOACs ... ) for VTE treatment ... prevention - Comparison Table ... #DOAC #Anticoagulants ... Anticoagulation #VTE
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... Currently, edoxaban ... filtration rate; DOAC ... #DOAC #VTE #Malignancy ... #Cancer #Algorithm
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Betrixaban (Bevyxxa), Edoxaban ... anticoagulation #doac ... #noac #pharmacology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
and bridging for VTE ... Clotmaster #VTE ... #DOAC #Bridging ... #Rivaroxaban #Edoxaban
Pharmacokinetic Characteristics and Primary Routes of Clearance of Oral Anticoagulant Agents

Warfarin - 100% Hepatic, 0% Renal
Apixaban
Hepatic, 80% Renal Edoxaban ... Hepatic, 35% Renal #DOAC ... #NOAC #Metabolism
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
Anticoagulants and DOACs ... Rivaroxaban, Apixaban, Edoxaban ... , Betrixaban, DOAC ... Anticoagulants #DOACs
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... Edoxaban is <2.5 ... #Warfarin #DOAC ... #Pharmacology #Table
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... : • Apixaban, Edoxaban ... not available #DOAC ... #Reversal #NOAC