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management diagnosis pharmacology treatment differential medications algorithm table causes syndrome diabetes endocrinology comparison nephrology pulmonary dm2 asthma pathophysiology toxicology buprenorphine
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... Action: Inhibits DPP ... GLP-I receptor agonist ... EricsMedicalLectures/featured #DPP4
Mechanism of Action for Common Diabetes Medications • SGLT2i (Dapagliflozin) • TZD (Pioglitazone) • Biguanides (Metformin)
GLP-1 Receptor Agonists ... • DPP4i / Gliptins
Oral Hypoglycemics in Diabetes Management 1 INSULIN SENSITIZER • TZD -
- PPAR gamma agonist ... AGENTS • GLP-1 agonists ... (Adlyxin) • DPP ... by inhibiting DPP
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
GLP-1 receptor agonists ... events TZDs DPP
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
First Oral GLP-1 Agonist ... only) oral GLP1 agonist ... injectable GLP1 agonists ... GLP1 agonists are ... empagliflozin and DPP4
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
GLP-1 Agonists ... Daily GLP-1 Agonists ... very similar to DPP4s ... #GLP1 #Agonists
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
kidney disease, DPP4i ... peptide- I receptor agonist
#diabetes #T2DM #antidiabeticagents #oraldiabeticagents FIGURE 9.1 Glucose-lowering medication in type 2 diabetes: overall approach. For appropriate context,
outcomes trials; DPP ... GLP-1 receptor agonist
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... GLP-1 receptor agonist
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Metformin + DPP4 ... dapagliflozin) Dpp4
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