282 results
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
metformin in T2D and CKD ... cardiovascular disease: CKD ... kidney disease, DPP4i ... , #KDIGO2020 #CKD ... Management in CKD
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
events TZDs DPP ... Improved outcomes in CKD
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
Definitions of AKI, CKD ... , AKD Acute Kidney ... Kidney Disease (CKD ... /CKD • No structural ... damage #AKI #CKD
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD EMPA-REG ... SGLT2i in HF and CKD ... SGLT2i in HF and CKD ... kidney events in CKD ... patients with CKD
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... Action: Inhibits DPP ... EricsMedicalLectures/featured #DPP4
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Metformin + DPP4 ... dapagliflozin) Dpp4
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... linagliptin) 5 mg DPP4 ... lower dose of a DPP4 ... /ambcarerx #DPP4
Oral Antihypertensive Medications - Selection by Comorbidities
Comorbidities: 
 • Stable Angina, HFpEF, HFrEF, AFib, TAA/Marfan, Aortic
Dissection • CKD ... , DM, ESRD, PKD
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
Clock for Staging CKD ... Staging CKD is ... calculating the eGFR, CKD ... cut-offs for each CKD ... Diagnosis #Nephro #CKD
Gout Management in CKD
 • Colchicine
 • NSAID
 • Glucocorticoid
 • ACTH
 • Interleukin-1 Inhibitors

#Gout #Management
Management in CKD ... Gout #Management #CKD