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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
of Acute Liver Injury ... #Diagnosis #Hepatology ... #Acute #Liver # ... Injury #Causes #Differential ... #Failure
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
liver failure ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential ... #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... liver failure rapidly ... infiltration) Differential ... Hepatitis, Preeclampsia ... #Pregnancy #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Diagnosis High ... - Alcoholic hepatitis ... Fulminant hepatic failure ... Veno-occlusive disease - Acute ... #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Failure ( ... Production: • Albumin ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
INR, bilirubin, albumin ... including R heart failure ... • Cirrhosis/acute ... hepatitis • Infiltrative ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... failure with coagulopathy ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
- Alcoholic hepatitis ... fibrosis - Acute ... Ascites #Causes #diagnosis ... #differential # ... hepatology #SAAG
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Total Protein - Albumin ... concentration minus albumin ... Sarcoidosis) • Liver ... Gap #ProteinGap #differential ... #diagnosis #hematology