7 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... smear: Blasts APML ... distinctive primary granules ... #Leukemia #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... unless severe APLS ... Differentiation #Syndrome #APML ... diagnosis #management #hematology
A quick infographic on various pearls about atopic dermatitis, a disease with an increasing burden on
the physical, mental ... dermatitis #eczema #dermatology ... Wigley AM, et al ... corticosteroids in dermatology ... Arch Dis Child.
A quick infographic on the importance of sun protection and the various results of sun damage
causes #diagnosis #dermatology ... Toxicol Appl Pharmacol ... Arch Dis Child. ... Kuriger JK, et al ... Kang S, Chien AL
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Exposure to heavy metal ... progression to AML ... Syndromes #diagnosis #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
relatives (if all ... procedures and dental ... Disorders #History #peds ... pediatrics #diagnosis #hematology