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diagnosis rheumatology lupus sle systemic classification management ana antibodies antinuclear bleeding cerebritis cns comparison criteria cryoglobulinemia cryoglobulins differential disease druginduced
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... Antiribosomal P, APLA ... • CAD APLA/LAC ... vein thrombosis Hematologic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Systemic Lupus Erythematosus ... Clinical Domains ... cutaneous lupus • Arthritis ... pericarditis • Hematologic ... Anticardiolipin IgG > 40 GPL
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... (for secondary APS
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Systemic lupus erythematosus ... Systemic lupus erythematosus ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... arthralgia, and arthritis ... systemic lupus erythematosus ... SLE), rheumatoid arthritis ... classification #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... Screening Tests for All ... metabolic or endocrine disorders ... ANA and RF (if clinical
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Evaluating Bleeding Disorders ... relatives (if all ... #History #peds ... pediatrics #diagnosis #hematology
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