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diagnosis rheumatology sle systemic classification management ana antibodies antinuclear arthritis bleeding cerebritis cns comparison criteria cryoglobulinemia cryoglobulins differential disease druginduced
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... SLE) Clinical ... , Seizure disorders ... (for secondary APS ... #Erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... lymphoproliferative syndrome Clinical ... Antiribosomal P, APLA ... • CAD APLA/LAC ... vein thrombosis Hematologic
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Erythematosus ... Clinical Domains ... pericarditis • Hematologic ... Anticardiolipin IgG > 40 GPL ... #Erythematosus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... erythematosus ( ... erythematosus ( ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... Erythematosus ( ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... hematological disorders ... (e.g. systemic lupus ... erythematosus ( ... classification #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus ( ... Screening Tests for All ... metabolic or endocrine disorders ... ANA and RF (if clinical
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... Evaluating Bleeding Disorders ... relatives (if all ... #History #peds ... pediatrics #diagnosis #hematology
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