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diagnosis rheumatology management sle classification erythematosus systemic algorithm antiphospholipid dermatology differential druginduced rash syndrome treatment workup acute ana anemia antibodies
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
autoimmune disorder ... ): • Lupus anticoagulant ... at least: • 1 clinical ... 1 of the three aPLs ... presence of 1 clinical
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... (for secondary APS ... CNS #neurology #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Criteria for Systemic Lupus ... Erythematosus Clinical ... pericarditis • Hematologic ... Anticardiolipin IgG > 40 GPL ... Erythematosus #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... lymphoproliferative syndrome Clinical ... Antiribosomal P, APLA ... • CAD APLA/LAC ... vein thrombosis Hematologic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... , Drug-induced Lupus ... , Drug-Induced Lupus ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... hematological disorders ... to Autoimmune Disorders ... (e.g. systemic lupus ... classification #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Vasculitis - Collagen disorders ... Autoimmune Vasculitis (lupus ... Rash: - ITP - APLS ... Algorithm #Causes #dermatology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Pancytopenia is a hematologic ... a decrease in all ... well as varying clinical ... that involves disorders
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