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diagnosis rheumatology sle erythematosus classification management ana antibodies antinuclear arthritis bleeding cerebritis cns comparison criteria cryoglobulinemia cryoglobulins differential disease druginduced
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Headache, Movement disorders ... , Seizure disorders ... (for secondary APS
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... Clinical Domains ... pericarditis • Hematologic ... Anticardiolipin IgG > 40 GPL ... Criteria #SLE #Systemic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... lupus erythematosus ... , Drug-induced Lupus ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... vein thrombosis Hematologic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Syndrome: • Clinical ... (e.g. systemic ... lupus erythematosus ... classification #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... months to years) Systemic ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... Screening Tests for All ... metabolic or endocrine disorders ... ANA and RF (if clinical
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... relatives (if all ... • Presence of systemic ... #History #peds ... pediatrics #diagnosis #hematology
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