11 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... leukemia (blood ... overt cytoplasmic granules ... #Auer #Rods #Acute ... #APL #APML #Pathology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... diagnosed with acute ... her peripheral blood ... also described in acute ... Path #BloodSmear #Blood
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... the peripheral blood ... ALL (Acute Lymphoblastic ... Blast cells - Blood ... distinctive primary granules
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... are typical for acute ... myelogenous leukemia ... (AML) that is most ... Path #BloodSmear #Blood
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
years old) - Acute ... lymphoblastic leukaemia ... School-aged - Acute ... Adolescence - Acute ... Malignant #Childhood #Peds
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... histamine in their granules ... translocation • Acute ... myeloid leukemia ... thrombocythemia • Acute
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia ... (T-PLL) not Acute ... Myeloid Leukemia ... (AML). ... Microscopy #Clinical #Blood
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Standard-Risk Acute ... Lymphoblastic Leukemia ... Cytarabine #ALL ... #Leukemia #Treatment ... oncology #pediatrics #peds
The hematopoietic tree and the resulting leukemias and lymphomas 
The hematopoietic tree refers to the hierarchical
organization of blood ... differentiate into all ... types of blood ... classified into acute ... Acute leukemias
Esophageal Variceal Bleeding - Scoping Summary
GENERAL PRINCIPLES OF MANAGEMENT (VARICEAL-B):
V - Vasoconstrictor therapy: (Octreotide 50mcg bolus
acquired/vasoactive meds ... outcomes Hayat et. al ... TEG -> dec. in blood ... presentation AL ... not initiate in acute