8 results
Presentation of malignant disease in children 
Pre-school (<5 years old) 
 - Acute lymphoblastic leukaemia
old) - Acute lymphoblastic ... leukaemia - ( ... leukaemia (ALL) ... leukaemia (ALL) ... Malignant #Childhood #Peds
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... overt cytoplasmic granules ... I see all of these ... promyelocytic #leukemia ... #APL #APML #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... leukemias > 20% ... Chronic leukemia ... ALL (Acute Lymphoblastic ... distinctive primary granules
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Standard-Risk Acute Lymphoblastic ... Leukemia Induction ... Cytarabine #ALL ... #Leukemia #Treatment ... oncology #pediatrics #peds
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
abundant cytoplasmic granules ... promyelocytic leukemia ... (APL) following ... decreased secondary granules ... Rods #AuerRods #APL
B-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Clinical
 - Primarily a disease of childhood, 75% <6 yo
 - Increased
B-Cell Acute Lymphoblastic ... Leukemia/Lymphoblastic ... iAMP21 - BCR-ABL-like ... #LBL #Acute #Lymphoblastic ... #Leukemia #Lymphoma
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
• Acute Lymphoblastic ... Leukemia (ALL) ... Acute Myeloid Leukemia ... (AML) • Chronic ... Myeloid Leukemia
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
of crystallized granules ... acute myelogenous leukemia ... (AML) that is most ... Rods #AuerRods #AML