8 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... pathophysiology #pharmacology ... #potassium #medications
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Adenosine, Magnesium, Potassium ... Classification #Pharmacology ... #cardiology
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
repolarizing eflux of potassium ... #Pathophys #Pharmacology ... #Cardiology #Antiarrhythmics
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... the cell, serum potassium ... the same site as potassium ... CaitEKulig #Digoxin #Pharmacology ... Pathophysiology #cardiology
Class III Antiarrhythmics - Potassium Channel Blockers - Indications and Side Effects
Amiodarone
 • Suppression of VT
Antiarrhythmics - Potassium ... Antiarrhythmics #Potassium ... Channel #Blockers #pharmacology ... #cardiology
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
130 mEq/L • Potassium ... transcellular shift ... NS #comparison #pharmacology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
repolarization CLASS 3 - Potassium ... inotropy) ACCP Cardiology ... Vaughan #Williams #Pharmacology ... pathophysiology #cardiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... repolarization CLASS 3 - Potassium ... inotropy) ACCP Cardiology ... Antiarrhythmics #Pharmacology ... pathophysiology #phases #cardiology