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Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Fevers • ... purpura: strong sign ... pulses, bruis, or blood ... Large Vessel: Blood ... #rheumatology #
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... purpura: Strong sign ... pulses, bruits, or blood ... #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic fever ... , Vasculitis (e.g ... arteritis • Bloody ... #joint #pain #differential ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... younger pts) Differential ... sensitize red blood ... Symptoms: High fevers ... hemolytic #anemia #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... noninflammatory Signs ... • Rheumatic fever ... #Diagnosis #MSK ... #rheumatology #
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Crossmatch takes ... S/sx: Fever, flank ... Sx include: fever ... RBCs (stored at 4C ... diagnosis #management #hematology