39 results
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
• Rickettsial diseases ... : • Still's disease ... • Crohn disease ... • Behcet disease ... Brucellosis Faget's Sign
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pain • Kawasaki Disease ... (Granulomatous disease ... atherosclerotic disease ... most important diseases ... purpura: strong sign
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
semiology of Cutaneous Vasculitis ... • Drug-induced vasculitis ... Connective tissue disease ... dermatology #semiology #signs ... pathology #lesions #differential
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... the Nikolsky sign ... includes Kawasaki disease ... or Nikolsky sign ... #Differential
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... Peripheral edema, Disease-specific ... , Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Systemic rheumatic diseases ... atherosclerotic disease ... most important diseases ... purpura: Strong sign
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Clinical: • Disease ... Constitutional: Fever ... exertion • Neurologic ... Diagnosis #Symptoms #Signs
Diseases of the Biliary Tract
Asymptomatic gallstones - Asymptomatic
Symptomatic gallstones - Biliary pain
Cholesterolosis of gallbladder - Usually
Diseases of the ... , Murphy sign Chronic ... pain, jaundice, fever ... pancreatitis #biliary #diseases ... #differential #
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Lyme Disease: Early ... arthralgia, headache, fever ... • Heralded by neurologic ... WuidQ #Lyme #Disease ... #diagnosis #signs
Approach to ECGs - Ischemia
MI = Biomarkers + ECG or echo/angiogram findings
Pathologic Q - 1/3 height
Equivalents / Don't Miss Signs ... bigger than QRS - deWinter ... T waves - starts ... triple vessel disease ... Interpretation #differential