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diagnosis rheumatology symptoms causes nephrology syndrome erythematosus management pulmonary renal sle systemic algorithm autoantibodies behcet bilateral blines blood cardiology classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pain • Kawasaki Disease ... (Granulomatous disease ... atherosclerotic disease ... most important diseases ... purpura: strong sign
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
Clinical: • Disease ... Constitutional: Fever ... exertion • Neurologic ... Subcutaneous nodules, lupus ... Diagnosis #Symptoms #Signs
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... Peripheral edema, Disease-specific ... , Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... (aPL) 30-45% Differential ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
• Rickettsial diseases ... : • Still's disease ... • Crohn disease ... • Behcet disease ... Brucellosis Faget's Sign
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: Fever ... Butterfly rash, Vasculitis ... pain (20%) Renal disease ... erythematosus #signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Systemic rheumatic diseases ... atherosclerotic disease ... most important diseases ... purpura: Strong sign
Approach to ECGs - Ischemia MI = Biomarkers + ECG or echo/angiogram findings Pathologic Q - 1/3 height
Equivalents / Don't Miss Signs ... bigger than QRS - deWinter ... T waves - starts ... triple vessel disease ... Interpretation #differential
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Syndrome Systemic disease ... skin injury) • Neurologic ... Disease: Lesions ... ) Differential Diagnosis ... diagnosis #management #signs
Bilateral B-Lines in case of Pneumonia on Lung POCUS Young healthy pt with fever/dyspnea. POCUS lung exam
healthy pt with fever ... immunosuppression, travel ... Differential Bilat ... interstitial lung disease ... partially seen shred sign
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