12 results
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
GravesDisease: ... the etiology Signs ... /Symptoms: - Pretibial ... GravesDisease #pathophysiology ... #signs #diagnosis
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
When present, symptoms ... , signs, and complications ... • "Vasomotor" symptoms ... von Willebrand disease ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
variability in disease ... mood - Primary treatment ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... but elevated as disease ... diagnosis #workup #hepatology
In order to better classify heart failure, the American College of Cardiology Foundation and the American
based solely on symptoms ... But now the ACC/ ... With treatment, ... structural heart disease ... or signs of heart
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
' disease) • Thyrotoxicosis ... ' disease is suspected ... ↑ AST/ALT • Treatment ... endocrinology #signs ... #symptoms #thyroid
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... • Bicytopenia Treatment ... #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology