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diagnosis hematology cop cryptogenic fungal hemeonc hemophagocytic hlh infections infectiousdiseases leukostasis lymphohistiocytosis mycoses organizing pneumonia potts sarcoidosis summary syndrome tb
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - 80% have fever ... WBC >100k, + lab signs ... Syndrome: • Pathophysiology ... TLS #diagnosis #management
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... pulmonary TB PE ... decreased reflexes Pathophysiology
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... Cough, dyspnea, fever ... steroids for severe disease ... #pulmonary
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary ... #Signs #Symptoms
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
conidia → Yeast → travel ... • Fever, cough ... Aspergillosis Pathophysiology ... • Isolated fever ... Fungal #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... ▪ Autoimmune diseases ... Presentation • Common Signs ... and Symptoms: ... Pathophysiology
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