25 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #management #algorithm
Cardiac Amyloid - Diagnosis, Signs, Symptoms and Management

Clinical Presentation
- exertional dyspnea
- peripheral edema
- exertional syncope
- peripheral
Cardiac Amyloid - Diagnosis ... and Management ... Clinical Presentation ... despite hx HTN) EKG ... pseudoinfarct pattern (Q-waves
STEMI Equivalents on ECG
 • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
J point • De Winter ... syndrome - J-point ... V2 • Wellens sign ... pain • Wellens sign ... #EKG #diagnosis
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic ... UnknownOrigin #workup #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... hyperthermia crisis (late sign ... • Serotonin syndrome ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
carotid sinus syndrome ... further guide management ... orthostatic vital sign ... Further diagnostics ... should be guided by clinical
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... Retroperitoneum and aorta ... conventional imaging (aorta ... Glucocorticoids (0.6 mg/kg ... #management #phenotypes
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... patients with clinically ... stimulation Clinical ... #management #neurology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology