19 results
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
include protein C deficiency ... Aldosterone Deficiency ... Reduced libido • Signs ... addisons #disease #endocrinology ... #diagnosis #signs
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
21-Hydroxylase Deficiency ... - Signs and Symptoms ... #Hydroxylase #Deficiency ... #Signs #Symptoms ... #diagnosis #endocrinology
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
Hyperthyroidism – symptoms ... and signs. ... Symptoms: Weight ... Palmar erythema, Graves ... #Endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
21-Hydroxylase Deficiency ... 21-OHD in the adrenal ... as "congenital adrenal ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: ... #FeedbackLoop #endocrinology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
Pathophysiology: • T4 deficiency ... pathophysiology #signs ... #symptoms #endocrinology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
Circulating galactose-deficient ... Deficiency in galactosylation ... Intussusception - Renal ... Pathophysiology #Diagnosis #Signs ... #Symptoms
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
into the left renal ... the abdominal aorta ... blood in left renal ... Pathophysiology #Signs ... #Symptoms #Urology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
diffuse goiter (Graves ... antibodies (TRAb) if Graves ... #differential #endocrinology ... #signs #symptoms