23 results
rheumatology treatment differential neurology oncology signs symptoms hemophagocytic hlh lymphohistiocytosis anemia aplastic apml behcet bullous caudaequina causes chronic cll common
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Scurvy - Actinic damage ... #hematology #rheumatology ... #nonpalpable #dermatology
Lynch Syndrome: • "CRC + Endometrial/Ovarian + Stomach + Urinary → Lynch Syndrome" • Autosomal Dominant,
Lynch Syndrome: ... Urinary → Lynch Syndrome ... Mismatch Repair Defect ... Microsatellite Instability (MSI ... #diagnosis #management
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Cauda Equina Syndrome ... prevent permanent damage ... suspected, immediate MRI ... #MSK #pathophysiology ... #diagnosis #symptoms
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Autoantibody-mediated damage ... dermis Clinical Signs ... Bullous #Pemphigoid #Diagnosis ... #Management #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... WBC >100k, + lab signs ... of end organ damage ... #TLS #diagnosis ... #management #hematology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... Multiple Sclerosis Diagnosis ... resonance imaging [MRI ... #management #neurology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... and endothelial damage ... and endothelial damage ... Differentiation #Syndrome ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... : HLH signs and ... #management #treatment ... #hematology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Optic Neuritis - Diagnosis ... and Management ... Unilateral • Signs ... R-G or B-Y • MRI ... #rheumatology #
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... - MRI: inflammation ... #Rheumatology # ... diagnosis #management ... #Dermatology
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