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endocrinology inhibitors agonists dosing glp1 management comparison medications metformin overview receptor renal sglt2 sulfonylureas
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Summary Mechanisms ... failure Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Summary table of mechanism of action, side effect and contraindications of commonly used diabetic drugs. #pharmacology
Summary table of ... of action, side effect ... commonly used diabetic ... #pharmacology #dm2 ... #diabetes #medications
Sulfonylureas - Pharmacology Summary Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... CKD Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... disease Common Side Effects ... Toxicities: • GI side effects ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... #Summary #DM2 # ... diabetes #endocrinology
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Summary Mechanisms ... ) Common Side Effects ... • Euglycemic diabetic ... #Summary #DM2 #
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
to treat Type 2 Diabetes ... Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #DM2 #Endocrinology
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