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diagnosis management signs differential gca algorithm anteriorischemicopticneuropathy arteritis behcet chronic cll disease erythematosus giantcell giantcellarteritis hematology leukemia lupus lymphocytic manifestations
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... 50%): Pleurisy / effusion ... Restrictive lung defect ... erythematosus #signs ... #rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
optic neuropathy (AION ... field: altitudinal defect ... Clinical manifestations ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... SIGNS/SYMPTOMS ... Signs and symptoms
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Motor and sensory deficits ... autoimmune disorders (Systemic ... Manifestations #diagnosis #neurology ... #symptoms #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
, neurologic, and ... Diagnosis = clinical ... signs/sx of inflammation ... them, but urgent rheumatology ... GCA #Temporal #Signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... the skin, neurologic ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... • M > F • Affects ... Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome Systemic ... association • M > F Clinical ... skin injury) • Neurologic ... diagnosis #management #signs ... #symptoms #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... preferentially affects ... • Bilateral signs ... and/or symptoms ... diagnosis #management #neurology
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