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workup anesthesia anesthesiology hepatology rheumatology causes classification hematology intraoperative neurology pathophysiology treatment vasculitis acromegaly aflp algorithm anemia autoimmune biliary block
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... less common, only affects ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... #Diagnosis #Management
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... Extrinsic Causes: • Liver ... AIHA: warm, cold, drug ... , spider/snake bites
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pathophysiology: • Defect ... postpartum): • Initial symptoms ... infiltration) Differential ... Diagnosis: Viral ... obstetrics #obgyn #diagnosis
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
failure PBC Signs ... and Symptoms: ... or higher • Liver ... bile ducts Differential ... , Sarcoidosis, Drug-induced
Clozapine Toxicology Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
effect on negative symptoms ... antipsychotic drugs ... metabolized in the liver ... Toxicology #Toxicity #Diagnosis ... #Pharmacology
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
Phos), CBC with differential ... or TSH level if symptoms ... monitoring (vital signs ... Drugs to avoid ( ... #Management #CriticalCare
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
most frequently affects ... : HLH signs and ... symptoms can mimic ... lymph node, or liver ... #management #treatment
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
anaphylaxis (→ 3-1) Drug ... hyperthermia crisis (late sign ... #Hyperthermia #Differential ... Anesthesiology #Anesthesia #Checklist ... #Diagnosis #Management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
and Management ... GH stimulates liver ... Differential Diagnosis ... pachydermoperiostosis, drugs ... MRI+contrast Management
High Central Neuraxial Block - Guidelines for Crises in Anaesthesia • Can occur with deliberate or accidental
local anaesthetic drugs ... • Symptoms are ... that may mimic signs ... Intraoperative #Checklist ... #Diagnosis #Management
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