7 results
Algorithm for Metformin Prescribing and Dosing in CKD
Dose Initiation - Immediate release:
 • Initial 500 mg
Algorithm for Metformin ... Prescribing and Dosing ... • If Gl side effects ... #CKD #pharmacology ... algorithm #diabetes #titration
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
Metformin - First ... gastrointestinal (GI) adverse effects ... form and consider using ... #Indications #Titration ... #Pharmacology #
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... titrate up to effects ... Inhibitors #Renal #Dosing ... #Pharmacology # ... Diabetes #DM2 #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... mitigated by slow titration ... EricsMedicalLectures/ #Metformin ... #Pharmacology # ... DM2 #diabetes #endocrinology
Metformin: Biguanide
Metformin is the first-line medication for treatment of type 2 diabetes. It is very effective
Metformin is the ... point for side effects ... Additionally, titrating ... 2000 mg/day) and using ... #Pharmacology #
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... has a similar titration ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology