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inhibitors medications management oral summary comparison dosing glp1 table classification combination combo dmii hypoglycemics inpatient mellitus pills receptor renal rybelsus
Mechanism of Action for Common Diabetes Medications • SGLT2i (Dapagliflozin) • TZD (Pioglitazone) • Biguanides (Metformin)
Medications • SGLT2i ... GLP-1 Receptor Agonists ... • DPP4i / Gliptins ... #pathophysiology ... #endocrinology
Diabetes Combination Tablets - Estimated A1c Lowering Metformin + DPP4 • Janumet (metformin + sitagliptin) •
Diabetes Combination ... Metformin + DPP4 ... Tablets #Oral #DM2 ... #Pharmacology # ... Pills #Endocrinology
Diabetes Medications Summary Table Insulin Lifestyle modifications Metformin Sulfonylureas GLP-1 receptor agonists - ↓ major adverse CV events TZDs DPP-4 inhibitors SGLT2 inhibitors -
GLP-1 receptor agonists ... events TZDs DPP ... -4 inhibitors SGLT2 ... comparison #management #endocrinology ... #dm2
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... GLP-I receptor agonist ... failure Common Side Effects ... #Summary #DM2 # ... diabetes #endocrinology
Oral Hypoglycemics in Diabetes Management 1 INSULIN SENSITIZER • TZD -
- PPAR gamma agonist ... Prandase) • SGLT ... (Adlyxin) • DPP ... #Management #pharmacology ... #DM2 #DMII #Classification
SGLT2 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
- Pharmacology ... ) Common Side Effects ... • Euglycemic diabetic ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... GLP-1 receptor agonist ... , SGLT2i, Meglitinide ... #Mellitus #DM2 ... #Medications #pharmacology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... class of anti-diabetic ... #Inhibitors #Pharmacology ... #Medications #DM2 ... #Diabetes #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
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