7 results
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Medications • SGLT2i ... Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... normally inactivates GLP ... failure Common Side Effects ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... -4 inhibitor, GLP ... receptor agonist, SGLT2i ... #Medications #pharmacology ... comparison #table #endocrinology
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
Effects on body ... Weight Loss + - SGLT ... Weight Loss ++ - GLP ... Weight Loss +++ - DPP ... weightgain #comparison #pharmacology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
GLP-1 Agonists ... Common side effects ... very similar to DPP4s ... #Pharmacology #Dosing ... Diabetes #DM2 #Endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Increase Incretins (GLP-I ... titrate up to effects ... only few side effects ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
) - First Oral GLP ... when compared to SGLT2 ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology