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diagnosis rheumatology signs differential management vasculitis algorithm anteriorischemicopticneuropathy autoimmune behcet centralretinalartery chronic classification cll crao erythematosus features gca giantcellarteritis hemophagocytic
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
optic neuropathy (AION ... field: altitudinal defect ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Kawasaki Disease ... Affects children ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Restrictive lung defect ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs ... #symptoms #rheumatology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
arrhythmias, congenital defects ... anti-coagulation • Hematologic ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... management #treatment #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... claudication, pulse deficits ... • Progressive symptoms ... vasculitis • Cogan syndrome
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vasculitis) - Affects ... • Cogan Syndrome ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Dermatomyositis Symptoms ... papules and Gottron sign ... ) • Shawl sign ... caused by toxic effects ... Myositis #Myopathy #rheumatology
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