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diagnosis differential hematology management rheumatology oncology signs treatment algorithm leukemia abnormal acute autoimmune bee behcet cancer chagas chronic enzymes features
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... : CNS manifestations ... • Tumor lysis syndrome ... ) CLL Symptoms:
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... Motor and sensory deficits ... #Optica #NMO #Manifestations ... #diagnosis #neurology ... #symptoms #signs
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Kawasaki Disease ... Affects children ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... • Richter’s Syndrome
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... nasal squamous cell ... leukoencephalopathy and systemic manifestations ... #neurology #noninflammatory
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Neurological Manifestations ... lesion Pott's Disease ... Reconstitution Inflammatory Syndrome ... focal neurological deficits ... focal neurological deficits
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Heavy Chain disease ... & Mu) Skin Manifestations ... et diutinum Neurologic ... Manifestations:
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Acute Retroviral Syndrome ... Acute Retroviral Syndrome ... nervous system manifestations ... Labs: • CD4+ T-cell ... ART to slow HIV disease
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
M > F Clinical Manifestations ... skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... diagnosis #management #signs ... #symptoms #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... • Or brainstem syndromes ... Afferent pupillary defect ... SIGNS/SYMPTOMS ... Signs and symptoms
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