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diagnosis differential management signs hematology vasculitis algorithm anteriorischemicopticneuropathy autoimmune chronic classification cll erythematosus features gca giantcellarteritis hemophagocytic hlh kawasaki leukemia
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
optic neuropathy (AION ... field: altitudinal defect ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Kawasaki Disease ... Affects children ... #Features #Signs ... #Symptoms #Diagnosis ... #Peds #Pediatrics
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... azathioprine #Behcet ... #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Restrictive lung defect ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... vasculitis • Behcet ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vasculitis) - Affects ... VASCULITIS: • Behçet ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... • Richter’s Syndrome
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... Sarcoidosis • Behcet ... disease • Infections ... Polychondritis #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... caused by toxic effects ... Myositis #Myopathy #rheumatology
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