11 results
diagnosis hematology algorithm causes classification disorders hemophagocytic hlh lymphohistiocytosis oncology aflp anemia biliary cholangitis chronic cirrhosis cll dili drug eosinophil
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... Extrinsic Causes: • Liver ... , spider/snake bites ... classification #hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... less common, only affects ... ongoing ↑ LFTs or symptoms ... Idiosyncratic #differential ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pathophysiology: • Defect ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... obgyn #diagnosis #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
failure PBC Signs ... and Symptoms: ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Diagnosis: HLH signs ... and symptoms can ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... with no early symptoms ... Physical Exam/Signs ... Leukemia #diagnosis #workup ... #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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