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diagnosis hematology management oncology algorithm signs arteritis causes chronic cll deficiency eosinophil eosinophilia erythematosus gca giantcell hemolytic hodgkins leukemia lupus
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... , spider/snake bites ... Diagnosis #causes #classification ... #hematology
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
- Coagulation disorder ... , neural tube defects ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... organ-specific signs ... #Algorithm #Differential ... #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... - Differential ... pattern of spread, B symptoms ... Responsive to Treatment ... #Classification
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... lymphoproliferative disorders ... • Neutropenia, anemia ... microglobulin Treatment
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... systemic complaints- anemia ... Treatment of GCA ... them, but urgent rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... age 70 years Symptoms ... Neutropenia • Platelet Disorders ... blood count with differential ... Syndromes #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
preferentially affects ... • Bilateral signs ... and/or symptoms ... Transverse Myelitis Treatment ... management #neurology #differential
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