12 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... : • Defect in fetal ... AP, ↑INR, ↑BUN/Cr ... ) Differential Diagnosis ... #management #pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
the posterior occipital ... may precede the neurologic ... Etiology: • Pathophysiology ... #diagnosis #management ... #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... common • Imaging: CXR ... Differentiation #Syndrome ... #management #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... Multiple Sclerosis Diagnosis ... objective evidence of neurologic ... #management #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... most frequently affects ... : HLH signs and ... #management #treatment ... #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Paraneoplastic effects ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... #management #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... and Management ... survival is 93-95% Pathophysiology ... e.g. incidental CXR ... #Management #Signs