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chronic cll differential differentiation hemeonc hemophagocytic hepatology hlh hypertension leukemia lymphocytic lymphohistiocytosis myelitis neurology polycythemiavera portopulmonary pv summary syndrome transverse
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... Differentiation #Syndrome #APML ... #diagnosis #management ... #hematology #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... Criteria: • Elevated ... present, symptoms, signs ... transformation into AML ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• M > F • Affects ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... #workup #oncology ... #hematology
Portopulmonary Hypertension Presence of pulmonary arterial hypertension in a patient with portal hypertension No other obvious causes (chronic
m/s • Other signs ... for definitive diagnosis ... Diagnostic criteria ... the vasodilatory effects ... #management #hepatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... preferentially affects ... Criteria: • Sensory ... • Bilateral signs ... #management #neurology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Presentation • Common Signs ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
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