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endocrinology agonists glp1 management summary allopurinol cardiology ddi diagnosis drugdrug herbal interactions medications oral otc pathophysiology pheochromocytoma receptor renal rybelsus
DPP-4 Inhibitors - Pharmacology Summary Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
DPP-4 Inhibitors ... failure Common Side Effects ... #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... titrate up to effects ... only few side effects ... #Dosing #Pharmacology ... #DM2 #Endocrinology
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
class of anti-diabetic ... include side effects ... Side effects include ... #Pharmacology # ... Medications #DM2
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Ozempic), or daily tablet ... pancreatitis Common Side Effects ... Toxicities: • Gl side effects ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Agonists Adlyxin (Lixisenatide) Daily Bydureon (Exenatide ER) Weekly Ozempic (Semaglutide) Weekly Trulicity (Dulaglutide) Weekly Victoza (Liraglutide) Daily
Common side effects ... very similar to DPP4s ... GLP1 #Agonists #Pharmacology ... #Dosing #Diabetes ... #DM2 #Endocrinology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products Angiotensin-Converting Enzyme Inhibitors (ACEIs) • Night-blooming
Cardiovascular Drug-Drug ... Angiotensin-Converting Enzyme Inhibitors ... Monoamine Oxidase Inhibitors ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Allopurinol Pharmacology Summary Xanthine oxidase inhibitor blocking the formation of new uric acid Initiate 1-2 days prior to
Xanthine oxidase inhibitor ... chemotherapy Dosing ... 10mL/min Side effects ... hypersensitivity Drug ... pathophysiology #gout
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist Dosing: 3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... to remain stable ... empagliflozin and DPP4 ... #semaglutide #Diabetes ... #Pharmacology #
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
Symptoms and Signs ... or with certain drugs ... monoamine oxidase inhibitors ... apparent type 2 diabetes ... the vasodilatory effect
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