32 results
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
flexion of the knees ... While the pathophysiology ... for the hip/knee ... is that hip and knee ... despite severe disease
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
• Brushfield spots ... iris (pigmented spots ... Congenital heart defects ... • Hirschsprung disease ... PhysicalExam #Features #Signs
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... #Disease #Tuberculosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... Afferent pupillary defect ... McDonald diagnostic criteria ... taper 3-7 days - Short ... sclerosis #diagnosis #management
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Diagnosis and Management ... Symptoms and Signs ... Diagnostic Criteria ... #criteria #Tropheryma
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... most commonly the knees ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs
Kawasaki Disease: Clinical Findings
Diagnostic Criteria - Fever and 4/5 of the following:
 • Conjunctivitis
 • Polymorphous
Kawasaki Disease ... Findings Diagnostic Criteria ... hands & feet Signs ... #Pathophysiology ... #Signs #Symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... : El Escorial criteria ... neurology #diagnosis #management
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... arrhythmias, congenital defects ... -> Cherry-red spot ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... Sickle cell disease ... almost exclusively affects ... The underlying pathophysiology ... Crisis #Features #Signs