Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious onset, becomes more constant as disease progresses) - X-ray: Blurring and pseudo-widening in Sl joints • Asymmetrical Oligoarthritis: mostly involving the lower extremities, most commonly the knees • Enthesitis: Tenderness over tendon insertion points, most prominently in Achilles, Plantar fascia, and tibial tuberosity • Decr Lumbar spine flexion, Decr Lumbar lordosis, Incr thoracic kyphosis, X-ray: loss of lordosis (straight spinal column) • Late complication: ankylosed spine (bamboo spine) -> Fracture of spine with minor trauma #AnkylosingSpondylitis #pathophysiology #diagnosis #signs #symptoms
