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differential hematology algorithm generalized oncology pruritus systemic hypothermia leukemia mds myelodysplasia myelodysplastic nonpalpable normocytic palpable pancytopenia purpura rheumatology syndromes thrombocytosis
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Causes of Neutropenia ... - Differential Diagnosis ... Infection • Primary ... Toxins • Aplastic Anemia ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... - Differential Diagnosis ... Reticulocytosis • Primary ... Hypersplenism • Secondary ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Post-splenectomy Primary ... #Causes #hematology ... #secondary
Secondary Causes of Hypothermia - Differential Diagnosis Framework Definition: - Core temp < 35°C Infectious: - Sepsis Neuromuscular Disease: -
Secondary Causes ... - Differential Diagnosis ... Definition: - Core ... Carcinomatosis - Uremia ... #Secondary #Causes
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Generalized Differential Diagnosis ... Causes == Primary ... renal failure/uremia ... #secondary #systemic ... #generalized #dermatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... - Differential Diagnosis ... drug reactions - Secondary ... Megaloblastic anemia-rare ... #causes #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... /Quantity: • Primary ... : ITP • Secondary ... - Hemolytic anemia ... #nonpalpable #dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP Score ... - infiltrates (anemia ... or functional neutropenia ... + distinctive primary ... #Oncology #Diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... #Pruritus #secondary ... #generalized #dermatology ... #Algorithm #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Myeloproliferative Disease • Neutropenia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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